The Glymphatic Pathway is the brain's waste-clearance system. Cerebrospinal fluid (CSF) flows through periarterial spaces, exchanges with interstitial fluid, and flushes metabolic waste (including beta-amyloid) out of the brain, primarily during deep sleep.
Key Points
- •Sleep-dependent — ~90% of glymphatic clearance occurs during deep sleep
- •Temperature — core temperature drop promotes clearance
- •Posture — lateral sleep position may enhance flow
- •Insulin — caloric intake before sleep can impair clearance
In ONDA Life
The Glymphatic Flush article covers sleep posture, thermal flush, and dietary firewall protocols for optimizing glymphatic clearance.