Biological SoftwareSCIENTIFIC TERM

HPA Axis

Hypothalamus-Pituitary-Adrenal axis — the body's central stress response system that releases cortisol.

What is HPA Axis?

The HPA axis (Hypothalamus-Pituitary-Adrenal) is the body's primary stress response system. When activated, it triggers the release of cortisol and other stress hormones, mobilizing the body for challenge.

The Pathway

  1. •Hypothalamus — releases CRH (corticotropin-releasing hormone)
  2. •Pituitary — releases ACTH (adrenocorticotropic hormone)
  3. •Adrenal glands — release cortisol (and adrenaline from the medulla)

Acute vs. Chronic

Chronically elevated cortisol is linked to harm, while short, acute rises in cortisol and adrenaline are a normal part of mobilizing energy and focus for a challenge.

In ONDA Life

Part 4 "Neuroendocrinology" works with the felt experience of stress: practising staying composed and precise under pressure. ONDA does not measure cortisol or any hormone, and makes no claim that its practices change hormone levels.