The locus coeruleus is a small nucleus in the brainstem that is the primary source of norepinephrine in the brain. It projects widely to the cortex, hippocampus, and cerebellum, regulating alertness, attention, and the stress response.
Key Functions
- •Alertness — modulates wakefulness and vigilance
- •Attention — enhances focus on salient stimuli
- •Stress response — activates under threat or challenge
- •Cognitive flexibility — supports task switching
In ONDA Life
Part 8 "Locus Coeruleus" regulates alertness levels through norepinephrine. The ACC monitors distractions and detects errors. Optimal locus coeruleus function supports sustained focus without burnout.
Scientific Basis
Built on: Polyvagal Theory (Porges); Psychoneuroimmunology (Ader & Cohen); neuroplasticity research.