Lipolysis is the breakdown of triglycerides in adipose tissue into free fatty acids and glycerol for use as energy. It is regulated by hormones including catecholamines (epinephrine, norepinephrine) and inhibited by insulin and prolonged cortisol elevation.
Key Points
- •Cortisol timing — evening cortisol elevation blocks lipolysis during the metabolic window when fat oxidation typically peaks
- •Insulin — high insulin suppresses lipolysis; fasting and low-carb states promote it
- •Sleep — deep sleep supports growth hormone release, which favors fat mobilization
In ONDA Life
The CHM article explains how cortisol sync and evening protocols support lipolytic windows.