The Glymphatic System is the brain's waste-clearance network, analogous to the lymphatic system for the rest of the body. It uses cerebrospinal fluid (CSF) to flush metabolic waste (including beta-amyloid) from brain tissue, primarily during deep sleep.
Key Points
- •CSF flow — periarterial inflow, interstitial exchange, perivenous outflow
- •Sleep-dependent — most active during slow-wave sleep
- •Glymphatic Pathway — the route of CSF through the brain; see the Glymphatic Pathway glossary entry for protocol details
In ONDA Life
The Phase-Locked Sleep and Glymphatic Flush articles cover protocols for optimizing glymphatic function.